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The P2Y11 receptor has a high affinity for ATP and the P2X7 a lower affinity.When intercellular concentrations of ATP are increased due to cellular damage caused bymassive cell death the low-affinity P2X7 receptor is activated, which leads to Ca++ influxthat induces calcineurin to dephosphorylate both NFAT and NFkB. Note that the surface coatofthesevesicles is different from that ofclathrin-coated vesicles.
Acupuncture and sham acupuncture consisted of twelve ses-sions per patient over a period of eight weeks.
Distraction osteogenesis in the treatmentof long bone defects of the lower limbs: effectiveness, complications and clinical results;a systematic review and meta-analysis.
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